New Treatment for Excessive Underarm Sweating
Orange County, CA - June 6th, 2018 - Primary axillary hyperhidrosis, also known as excessive underarm sweating, affects an estimated 15 million people in the United States, according to a study. Of the 15 million, 65 percent of people suffer from localized sweating to the underarms (axillary disease).
The body’s mechanism for cooling itself is overactive, meaning people sweat five times more than what is necessary. Studies have shown that excessive sweating hinders regular daily activities, and can result in emotional, psychological, social, and physical impairment.
Most people are never diagnosed or relieved of their symptoms. The treatment options are currently surgery, Botox injections, and off-label use of drugs that block the body’s chemical messengers.
Dermira, a Silicon Valley firm, has won the U.S. Food and Drug Administration’s (FDA) approval for the first once-daily, topical prescription treatment named “Qbrexza”. It is indicated for adult and pediatric patients (9 years of age and older) who suffer from excessive underarm sweating.
The approval is based on the results of two Phase 3 clinical trials, ATMOS-1 and ATMOS-2, which evaluated the efficacy and safety of Qbrexza in patients with primary axillary hyperhidrosis. Both trials demonstrated a significant improvement for both co-primary endpoints and both secondary endpoints.
The most frequently reported side effect was dry mouth. Other possible side effects include dryness of the skin, eyes, nose, and throat; with possible headaches, blurred vision, dilated pupils, constipation, or trouble urinating.
The treatment comes in the form of a cloth soaked in glycopyrronium, an anti-cholinergic, which is a chemical that blocks receptors that help activate sweat glands. The treatment doesn’t need to be administered by a physician. Once prescribed, it's up to the patient to apply the treatment one time, each day.
Qbrexza is expected to be available nationwide in pharmacies beginning in October 2018.
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New Treatment for Excessive Underarm Sweating Orange County, CA – June 6th, 2018 – Primary axillary hyperhidrosis, also known as excessive underarm sweating, affects an estimated 15 million people in the United States, according to a study. Of the 15 million, 65 percent of people suffer from localized sweating to the underarms (axillary disease). The body’s mechanism […]